(DOWNLOAD) "Heterocycle Synthesis Via Radical Reactions * (Report)" by Pure and Applied Chemistry * eBook PDF Kindle ePub Free

February 20, 2021

eBook details

Title: Heterocycle Synthesis Via Radical Reactions * (Report)
Author : Pure and Applied Chemistry
Release Date : January 01, 2008
Genre: Chemistry,Books,Science & Nature,
Pages : * pages
Size : 171 KB

Description

Abstract: A novel synthetic method for the preparation of nitrogen-containing heterocycles via the route involving domino-type radical addition/cyclization reaction of oxime ethers is described. Alkyl radical addition/cyclization of oxime ethers carrying an appropriate leaving group proceeded smoothly to form the alkylated nitrogen-containing heterocyclic compounds. Additionally, tin-mediated radical addition/cyclization/elimination (RACE) reaction of oxime ethers is newly found and successfully applied to an asymmetric total synthesis of (--)-martinellic acid. Keywords: radical reaction; oxime ethers; domino reaction: bgugaine; martinellic acid.